Description
What it is
A research blend pairing the FDA-approved GHRH analog Tesamorelin with the selective GH-releaser Ipamorelin — targeting both arms of the GH axis simultaneously.
Why it’s studied
The combination stimulates GHRH receptors (via Tesamorelin) and ghrelin receptors (via Ipamorelin) in parallel, a dual-receptor approach well-documented for amplifying IGF-1 response.
Key research findings
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Tesamorelin: 15-18% reduction in visceral adipose tissue at 26 weeks (Falutz et al.)
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Ipamorelin: clean GH release without cortisol/prolactin (Raun et al.)
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Dual-receptor stimulation documented to amplify IGF-1 response beyond either alone





