Description
What it is
The coenzyme behind every mitochondrial energy reaction in the body — and central to virtually all longevity research published in the last decade.
Why it’s studied
NAD+ levels decline approximately 50% by age 50, and this decline is implicated across nearly every hallmark of aging. Restoration of cellular NAD+ pools is at the core of modern longevity science.
Key research findings
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~50% decline in NAD+ levels by age 50 (Massudi et al., human tissue analysis)
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Central cofactor for sirtuin enzymes and DNA repair pathways
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Documented role in mitochondrial function across longevity research
