Description
What it is
The most-studied dual stack in growth hormone research — pairing a GHRH analog with a selective GH-releaser to target two receptors on the same pathway.
Why it’s studied
CJC-1295 amplifies natural GH release pulses while Ipamorelin selectively triggers GH without affecting cortisol, prolactin, or appetite. The two peptides hit complementary receptors, producing synergistic IGF-1 elevation.
Key research findings
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Synergistic IGF-1 elevation beyond either compound alone (Teichman et al., CJC-1295 trials)
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Ipamorelin: clean GH release without cortisol or prolactin elevation (Raun et al.)
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Preserved natural pulsatile release patterns when used in combination
